UNCERTAINTIES IN MATHEMATICAL MODELS AND INVERSE PROBLEMS Aleksey V. Nenarokomov', Ashley F. Emery", Tushar D. Fadale''' 'Moscow Aviation Insitute Moscow, Russia "University of Washington Seattle, WA, USA '''Applied Research Associates Raleigh, North Carolina, USA A large class of promising methods for the analysis and interpretation of data from transient thermophysical experiments is based on the solution of the inverse heat conduction problems. In this approach the coefficients (thermophysical characteristics) in the heat conduction equation are determined from the known boundary and initial conditions and from the data of transient temperature measurements at a finite number of spatially distributed points of the analyzed body. The chief advantage of these methods is that they enable us to conduct experimental investigations and tests under conditions as close to nature as possible, or directly during operation of engineering devices. Features of ill-posed inverse heat transfer problem require special mathematical methods for solving them as well as a proper technical organization of the studies. Only a rational combination of physical combination of physical, mathematical and technical fundamentals make it possible to effectively use these methods in practice. Mathematical modeling data show that the error of determination of the thermophysical characteristics from the solution of the inverse problem may depend significantly on the spatial placement of the temperature sensors in the investigated body. The proper setup of the thermophysical experiment requires the solution of an optimal experimental design problem, i.e. to place a fixed number of sensors in the sample in such a way as to minimize the error of identification of the required characteristics. The stated problem can be solved on the basis of the fundamental principles of experimental design theory for distributed-parameter system. The information matrix characterizes the total sensitivity of the analyzed system in the entire set of measurement points to the variation all components of unknown functions. The given optimal measurement design problems entails finding positions of sensors for with the total sensitivity of the system in the adopted sense will be a maximum. Various criteria are used for the optimization of the experimental conditions. The so-called D-optimum design is widely used to ensure the minimum error of estimation of the unknown functions. In this case the measurement design can be determined from the condition of the maximum of the determinant of the normalized information matrix.